Any suggestions to help a middle aged person quit cannabis? They smoked in late teens and 20’s. Quit for about 12 years and then vaped for about 4 years during their mid 40’s. Anything good for stopping cravings and rebuilding brain? They are trying phenibut with mixed results so far. 1st day went well, 2nd day no pot cravings but exceedingly tired and lethargic. So they will try reducing phenibut dose from 1 gram to 300 mg. They know to be careful with phenibut and plan not to do it daily, but are desperate to get off pot which has been prescribed to them (for anxiety etc) but is causing many problems. TY

Reply 1 Rhodolia helps the body deal with stress, and emotional proccessing.
Reply 2 CBD (oral, topical, vaporized, etc) offers much faster relief compared to an SSRI drug, which may take weeks to months to take effect In comparison.
Reply 3  I second the recommendation for CBD. Just kick out the THC and it might be easier to step down since CBD will quell anxiety. Cannabis isn’t physically addictive, only habit-forming if the person isn’t doing anything to work on themselves like meditation, yoga, spiritual practice of some sort. If memory is an issue, Gota Kola and Ginkgo are some herbs that can be helpful.
Reply 4 I know it’s easier said than done, but just quit buying weed and forget the substitute all together. The cravings go away and chemistry wise most things you’d take for anxiety for replacement are going to leave you worse off than the weed. But I had really great results curing social anxiety with a change of mindset and took 200-600mg of l-theanine for about 3 weeks to take the edge off some of the physical symptoms. I think knowing I had the crutch while I actively got more socially involved did more than the theanine itself though, if I was hard pressed I can’t tell you what if anything it actually did for me lol

Reply 5  Phenibut isn’t going to help rebuild jack crap. It will deplete it worse than cannabis
In my experience, phenibut gives me the ability to push my anxiety away, which is a new experience for me. So, it is useful in that respect, but coming off of it is not so much fun. The biggest problem I have is when I have something coming up the next day and I can’t sleep, or something is really bothering me and I can’t sleep. I hate that, so phenibut is good in those instances.
Reply 6  All ingested substances interfere with homeostasis. Synaptic plasticity occurs resulting in unwanted side effects following cessation. Many of us know this as addiction and withdrawl. Just as the human brain maintained homeostasis when the substance wa…See More
Reply 7  Something for sleep, new hobby/fun, typical regeneration stack uridine, noopept, choline, herbals, omega 3, dopamine/serotonine precursors. HOBBY shoting, bow, running anything watch anime and play games but dont smoke this shit. How is this possible to get addiced to weed? WTF, people tried heroin, benzodiazepines and a lot stronger things and dosent get addicted so how did they do that? Curcumine, EGCG, (5-htp, l-dop) Reply 8  The talks I’ve listened to regarding medical cannabis by some people knowledgeable in that area (I.e., Ethan Russo, Michael Backes, Mara Gordon among others) express the viewpoint that the amounts required to achieve a “high” are not necessarily required for medical efficacy. One must start out low and determine their own minimum effective dose. Using high doses for prolonged periods will create adverse effects and tolerance, due to desensitization and down regulation of cannabinoid receptors, which will lead to the user engaging in subsequent increases in dose.

Micro-dosing as a medical option has been examined through research in Israel. While controversial, and in need of further research, it has shown anecdotal benefits to mood and motivation.

Also, different strains’ terpene profiles, acting in synergy with cannabinoids, will have different effects (e.g., stimulating, sedating, etc.).

If you’re looking for neuroprotective and strong anti-inflammatory properties, the acidic (not decarboxylated) cannabinoid THCA is also an option as it isn’t psychotropic. The best bioavailability is when it is used through sublingual administration with a tincture.

Repy 9 Cannabis only increases the chance of developing mental illness if you’re already genetically predisposed to it, (it runs in the family.) Cannabis does not cause hallucinations, as only serotonin receptor agonists (such as LSD, Mescaline and Psilocybin) are capable of that. Cannabis has actually been reported to help symptoms of HPPD, not cause it.

Reply 10  I had mild to moderate gastrointestinal distress on cannabis cessation (no appetite vomiting, diarrhea) which is annihilated with daily tolerance reducers Agmatine, Memantine, Magensium, Bacopa & Omegas, and to potentiate (keep weed doses low and thus keep tolerance at bay) I also use Selegiline, moclobemide, black pepper, myrrh, frankincense & kanna. The tolerance reducers also potentiate the high by A LOT
Reply 11 With nanomolar affinity (strong). Copaiba essential oil is like 50% caryophyllene so like 5x more than black pepper essential oil. I mainly toss n wash pepper and probably get more CYP enzyme inhibition which is a different way to potentiate most drugs, by slowing their clearance from the body. Grapefruit does this too
Reply 12  There is a very high chance they are using too much and simply need to dial back the dosage. Marijuana rebuilds neurons and is associated with no negative effects on the body or brain according to the latest research except for slightly higher cases of peridontal disease from smoking but not vaping. As the body ages the ideal dose goes down. What they could consume in a night in their 20s may take a week in their 50s. It is common that people don’t adjust their dose and thus begin to experience negative symptoms. It is a curved benefit and efficacy curve …too little or too much is ineffective just right is good. Start low and go slow is the mantra.

Reply 14 In my experience most people who become dependent on cannabis have an underlying condition which is relieved by smoking – depression, anxiety, pain, etc… Sometimes the best approach is not to quit cannabis, but to find strains and dosage formats that do not cause the side effect of being “stoned”. For example: I was a chronic pothead in my teens and early 20s, and I stopped because I wanted to be more productive at work. Unfortunately my anxiety disorder got far worse after quitting pot, and I ended up hooked on opiates (which i was using to self medicate for anxiety.) I quit the opiates and these days I take an oral extract of specific cannabis strains that treats depression and anxiety better than any prescription drug known to man, but is completely free from psychoactive side effects – it contains only 2mg THC per dose but thanks to the terpenes and other cannabinoids in the plant, this is enough to achieve symptom relief (as you may know, it takes at least 10mg of THC to get ‘high’, so side effects are not an issue when using this product in a therapeutic dose.
Reply 15  I’ve taken tolerance breaks before, like vacations, etc. after 3 or 4 days you don’t desire it so much. After a week or so you’ll notice energy. Focus on a healthy diet like fruit smoothies for nutrients and take zinc. That usually helps me get some good energy and spiritual feeling (maybe it affects serotonin somehow?)